Benadryl Syrup: View Uses, Side Effects, Price – Full Guide

Benadryl Syrup is a well-known over-the-counter medication that has been a staple in many households for decades. It’s often the go-to solution for a variety of allergy symptoms, including sneezing, itching, and congestion. This article explores the many uses, side effects, and important information you need to know about Benadryl Syrup. Whether you’re considering using it for the first time or want to learn more about this common antihistamine, we’ve got you covered.

Understanding Benadryl Syrup

What is Benadryl Syrup?

Benadryl Syrup is a brand name for a medication that contains diphenhydramine, an antihistamine. Antihistamines work by blocking the action of histamine, a natural substance produced by the body when it encounters an allergen. Histamine is responsible for the symptoms of allergies, such as sneezing, itching, and a runny nose.

Benadryl Syrup comes in liquid form, making it easier to administer, especially for children who may have difficulty swallowing pills. This liquid formulation is convenient for individuals who may have trouble with tablets or capsules.

Uses of Benadryl Syrup

  1. Allergy Relief: Benadryl Syrup is primarily used to relieve allergy symptoms. It can help alleviate sneezing, runny nose, itching, and watery eyes, which are common reactions to allergens like pollen, dust mites, pet dander, and more.
  2. Common Cold: It can also be used to manage symptoms of the common cold, including congestion and a runny nose. However, it’s essential to understand that Benadryl Syrup may not treat the underlying cause of the cold but can provide temporary relief.
  3. Skin Allergies: In addition to oral use, Benadryl Syrup can be applied topically to relieve itching and discomfort associated with various skin allergies and irritations like insect bites, rashes, and hives.
  4. Insomnia: Some individuals use Benadryl Syrup as a sleep aid due to its sedative effects. It can help promote drowsiness and improve the quality of sleep. However, it’s important to use it as a sleep aid only under the guidance of a healthcare professional.
  5. Motion Sickness: Benadryl Syrup can be used to manage motion sickness symptoms, such as nausea and dizziness, but there are more specific medications available for this purpose.

How Does Benadryl Syrup Work?

As mentioned earlier, Benadryl Syrup contains diphenhydramine, an antihistamine. When you come into contact with an allergen (a substance that causes allergies), your body releases histamine, which leads to allergic symptoms like itching, sneezing, and a runny nose. Diphenhydramine works by blocking the action of histamine, thus reducing or preventing these symptoms.

It’s important to note that while Benadryl Syrup can relieve allergy symptoms, it does not cure allergies or address the root cause. It offers temporary relief from discomfort and allows you to manage the symptoms more effectively.

Using Benadryl Syrup

Dosage and Administration

When using Benadryl Syrup, it’s crucial to follow the recommended dosage instructions provided on the product label or as prescribed by your healthcare provider. The appropriate dosage can vary depending on your age, weight, and the condition being treated.

Typically, the dosing for Benadryl Syrup is as follows:

  • For adults and children 12 years and older: 2 to 4 teaspoons (10 to 20 mL) every 4 to 6 hours, not exceeding 24 teaspoons (120 mL) within 24 hours.
  • For children 6 to 11 years: 1 to 2 teaspoons (5 to 10 mL) every 4 to 6 hours, not exceeding 12 teaspoons (60 mL) within 24 hours.
  • For children 2 to 5 years: 1/2 to 1 teaspoon (2.5 to 5 mL) every 4 to 6 hours, not exceeding 6 teaspoons (30 mL) within 24 hours.
  • For children under 2 years: Consult a healthcare professional before using.

It’s essential to use the provided measuring device, such as a special dose-measuring spoon or cup, to ensure accurate dosing. Avoid using a regular kitchen spoon, as it may not provide the precise measurements required.

Precautions and Safety Measures

Before using Benadryl Syrup, consider the following precautions and safety measures:

  1. Allergies: If you are allergic to diphenhydramine or any other ingredients in the product, do not use Benadryl Syrup.
  2. Medical Conditions: Inform your healthcare provider if you have any pre-existing medical conditions, particularly respiratory conditions like asthma, glaucoma, high blood pressure, thyroid problems, or prostate problems. They can help determine if Benadryl Syrup is safe for you.
  3. Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, consult your healthcare provider before using Benadryl Syrup. While it’s generally considered safe, your healthcare provider can provide specific guidance based on your individual circumstances.
  4. Driving and Operating Machinery: Benadryl Syrup can cause drowsiness and impair your ability to drive or operate heavy machinery. Avoid such activities until you know how the medication affects you.
  5. Alcohol: Avoid consuming alcohol while taking Benadryl Syrup, as it can enhance the sedative effects of the medication.
  6. Interactions: Some medications can interact with Benadryl Syrup, including other antihistamines, sedatives, tranquilizers, and certain drugs for depression, anxiety, or seizures. Inform your healthcare provider about all the medications you are taking to avoid potential interactions.

Side Effects of Benadryl Syrup

While Benadryl Syrup is generally safe when used as directed, it may cause side effects in some individuals. Common side effects can include:

  • Drowsiness
  • Dry mouth
  • Dizziness
  • Blurred vision
  • Constipation
  • Upset stomach

These side effects are typically mild and temporary. However, if you experience severe side effects or allergic reactions (such as rash, itching, swelling, severe dizziness, or difficulty breathing), seek immediate medical attention.

Overdose and Emergency Situations

Taking more than the recommended dose of Benadryl Syrup can lead to an overdose, which can be life-threatening. Symptoms of an overdose may include:

  • Severe drowsiness
  • Confusion
  • Hallucinations
  • Seizures
  • Trouble breathing
  • Fast or irregular heartbeats
  • Loss of consciousness

If you suspect an overdose, call emergency services immediately. In the United States, you can contact the Poison Help line at 1-800-222-1222 for guidance.

Special Considerations for Children and the Elderly


Benadryl Syrup can be used in children, but the dosing should be carefully observed. Overdosing can be more dangerous for children, so always follow the dosing instructions provided and consult with a pediatrician if you have any concerns.


Elderly individuals may be more sensitive to the sedative effects of Benadryl Syrup. It’s advisable for older adults to use this medication with caution and under the guidance of a healthcare provider.

Storage and Disposal

When storing Benadryl Syrup, keep it in a cool, dry place away from direct sunlight and heat. Ensure that the bottle is tightly closed to prevent contamination. Keep it out of the reach of children and pets.

If you have expired or unused Benadryl Syrup, dispose of it safely. You can ask your pharmacist for instructions on proper disposal methods.

Frequently Asked Questions (FAQs)

1. Is Benadryl Syrup available without a prescription?

Yes, Benadryl Syrup is an over-the-counter (OTC) medication, which means it is available without a prescription. You can purchase it at most drug stores, supermarkets, or online.

2. Can I use Benadryl Syrup for my pet’s allergies?

Benadryl (diphenhydramine) can be used for certain allergies in dogs and cats under the guidance of a veterinarian. However, the dosing and administration must be determined by a veterinary professional, as it can vary based on the animal’s size and condition. Do not give Benadryl to your pet without consulting a vet.

3. Can I take Benadryl Syrup with other allergy medications?

Using multiple allergy medications simultaneously can increase the risk of side effects and interactions. It’s essential to consult with a healthcare provider before combining Benadryl Syrup with other allergy medications to ensure it is safe and effective.

4. How quickly does Benadryl Syrup work?

Benadryl Syrup typically starts to work within 15 to 30 minutes of administration. However, the onset of action may vary among individuals.

5. Can I drink alcohol while taking Benadryl Syrup?

Combining Benadryl Syrup with alcohol can increase drowsiness and impairment. It is advisable to avoid alcohol while taking this medication.

6. What should I do if I miss a dose of Benadryl Syrup?

If you miss a dose of Benadryl Syrup, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

7. Can Benadryl Syrup be used for chronic allergies?

Benadryl Syrup is best suited for short-term relief of allergy symptoms. If you have chronic or recurring allergies, consult with a healthcare provider. They can help you find a more suitable long-term treatment plan.


Benadryl Syrup is a versatile medication that provides relief from a range of allergy symptoms, common cold symptoms, and skin irritations. Its antihistamine properties make it an effective choice for managing discomfort associated with allergies. However, it’s crucial to use this medication responsibly, following recommended dosages and safety guidelines.

While Benadryl Syrup is generally safe, it may cause side effects in some individuals, and misuse or overdose can be harmful. If you have any questions or concerns about using Benadryl Syrup, consult with a healthcare provider or pharmacist. They can offer personalized guidance to ensure your safety and effectiveness in managing your specific health needs.

Remember that this article serves as a general guide and does not replace professional medical advice. Always consult with a healthcare provider for individualized recommendations and treatment plans. Whether you’re seeking relief from seasonal allergies, skin irritation, or a common cold, Benadryl Syrup can be a valuable tool in your healthcare arsenal when used responsibly and as directed.

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